Analysis Note

ControlRat E18 primary cortex cells

Application

Research Sub CategoryNeurodegenerative Diseases

Research CategoryNeuroscience

Evaluated by Immunohistochemistry in adult rat brain tissue.

Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Alzheimer Precursor Protein A4 in adult rat brain tissue.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Deposits of amyloid protein in senile plaques near nerve processes are found in the brains of aged humand and cases of Alzheimer′s Disease. The principle component of this extracellular amyloid is beta A4, a 4 kDa peptide derived from a larger amyloid precursor protein (APP), which is widely expressed in the brain and body. The creation, transport and function of these proteins is currently an active area of research.

Immunogen

Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein

Epitope: N-terminus

Physical form

Protein A purified

Purified mouse monoclonal IgG1 conjugated to Biotin in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Quality

Evaluated by Immunocytochemistry in rat E18 primary cortex cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Alzheimer Precursor Protein A4 in rat E18 primary cortex cells.

Specificity

This antibody recognizes Alzheimer Precursor Protein A4 at the N-temrinus.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

Varies